A woman was shot dead in Sheffield in the early hours of Bank Holiday Monday.
Police were called to a shooting outside One Four One bar on West Street at roughly 2.45am.
The woman, 30, was taken to hospital with serious injuries - where she later died.
Three people have been arrested on suspicion of murder, South Yorkshire Police said.
A 30-year-old man and 32-year-old woman were arrested near Stockport during the early hours of Monday, while a 30-year-old man was arrested in Sheffield.
All three remain in custody.
Read more from Sky News:
Former SNP chief executive Peter Murrell pleads guilty to embezzling £400k
The downfall of ex-SNP chief executive Peter Murrell
West Street is the hub of nightlife in the city, and is popular with students from the nearby University of Sheffield.
Assistant Chief Constable Colin McFarlane said the incident was "devastating" and paid tribute to the woman, who was on a night out when she was killed.
He went on: "First and foremost, our thoughts are with her family and everyone who knew and loved her.
"A man and woman were arrested near Stockport in Greater Manchester early this morning and a further man has been detained here in Sheffield.
"Our officers have been working extremely hard to piece together the events surrounding the shooting. While our investigation is in its early stages, we will continue to have a significant presence at the scene in the area today and in the coming days.
Mr MacFarlane pleaded with witnesses to come forward, adding "Now is not the time to stay silent."
"Gun crime causes unbearable tragedy and the victim and her family deserve answers. We will work tirelessly to provide these answers and to put those responsible before the courts."
(c) Sky News 2026: Woman shot dead in Sheffield city centre on Bank Holiday Monday
Nicola Sturgeon denies any knowledge of items husband Peter Murrell bought with embezzled £400,000
Human skeletal remains found in wooded area
Why an industry that brought £8.8bn to UK economy last year faces uncertain future
Operation Branchform timeline: The downfall of ex-SNP chief executive Peter Murrell
Cheese-rolling legend beaten by German YouTuber
More than 20 people taken to hospital after unknown substance sprayed in Tokyo
Boy, 16, seriously injured after 'horrific' machete attack
China launches three-astronaut rocket into space as new lunar race intensifies
