A 47-year-old New Jersey man died last year from alpha-gal syndrome, a red meat allergy caused by a tick bite.
His death is believed to be the first documented death from a meat allergy triggered by tick bites.
Symptoms for alpha-gal syndrome - which in 2011 was first linked to bites from the Lone Star tick - can include hives, nausea, vomiting, diarrhoea, severe stomach pain, difficulty breathing, dizziness and swelling of the lips, throat, tongue or eyelids.
The reaction to the foods that cause the symptoms can be delayed, and usually present themselves a few hours later, unlike some other food allergies, which occur soon after eating.
The new research follows the case of a healthy airline pilot who went camping in 2024 with his wife and children. They had steak for supper. This was unusual, as he rarely ate meat.
He woke at 2am with violent pain in his abdomen, vomiting and diarrhoea.
The next day he ate breakfast and went on a five-mile walk.
A fortnight later, back in New Jersey, he went to a barbecue, where he ate a hamburger. About four hours later, he grew ill. Shortly afterwards, his son found him on the bathroom floor unconscious.
His son called paramedics, and he was admitted to hospital, but the man was announced dead later that night.
Blood tests conducted by researchers revealed evidence of the alpha-gal syndrome. Proof that it came from a Lone Star tick is inconclusive.
The researchers made the link after a statement from the man's wife, who had said he had 12 or 13 "chigger" bites near his ankles earlier in the summer.
But the conclusion makes sense, as people in eastern America sometimes mistake the bites from mites with those from larval ticks.
More than 100,000 people in the U.S. have become allergic to red meat since 2010 because of the syndrome, according to one estimate.
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Dr Scott Commins, a leading alpha-gal syndrome researcher at the University of North Carolina, called his death an "unmitigated tragedy".
"Totally unnecessary and with increased awareness, this won't happen again," he said in an email.
(c) Sky News 2025: A US man is believed to be the first to have died from a meat allergy linked to tick bites
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