Boro take on North East 2 bottom side Doncaster Phoenix as they aim to continue their excellent season so far.
Matty Jones' men sit fourth in the division but hopes will be high for the hosts at Silver Royd.
In Yorkshire One, Bridlington are also at home, against Hullensians, at Dukes Park.
In North East 1, Driffield are on their travels at Halifax side Heath.
Hornsea are also away as they look to keep up their title challenge, at Leeds Medics and Dentists, in Yorkshire 4 North.
Whitby make the long trip to Wallsend in Durham & Northumberland Division Three.


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