A section of the the A64 will be closed from 8pm on Friday.
Both the eastbound and westbound carriageways will be closed between Brambling Fields to East Heslerton.
The road will be closed from 8pm on Friday October 9th until 6am on Monday October 12th.
The carriageway closures are to enable carriageway improvement works to be carried out.
Highways England say a diversion route will be in place.
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High: 15°C | Low: 9°C
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The Met Office says thunderstorms and heavy downpours may cause flooding and travel disruption on the Yorkshire Coast on Bank Holiday Monday.
Four men have been charged on the Yorkshire Coast by National Crime Agency officers investigating the attempted importation of cocaine with a potential street value of around £40 million.
There's concern over the distances hospital patients are being asked to travel for surgery- particularly people from Bridlington.